Scientists from the UK were able to determine why women in the age there are problems with childbirth and why they often are born with birth defects in children .
If a woman over 40 is decided to have a baby, the risk of infertility or miscarriage she is significantly higher than in women younger. In addition, such women grow and the risk of having a baby with birth defects . Down syndrome or other genetic diseases. It has long been known, but until recently, the science does not know exactly what can be explained by a similar connection.
A team of scientists from Newcastle University and Newcastle Fertility Research Center found that with age, the body in women drops sharply protein level kohezina which helps the eggs to prepare for the moment of fertilization. The fall of this level increases the danger that the egg would be erroneous number of chromosomes.
This discovery could lead to a new generation of drugs that will help keep the egg in a healthy condition in women. "Reproductive health in women after 35 deteriorates very significantly, - says study author Dr. Mary Herbert. - We have conducted a study on mice where the adult mice were the equivalent of women after the age of 40. The level of protein kohezina in the body of mice dramatically reduced, resulting in a process of dividing chromosomes proceeded with serious anomalies. We will have more research to determine why age has an impact on kohezin. "
Pregnancy and Gynecology
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