Problems with sleep at night, often lead to fatigue and irritability. But those who are faced with these problems regularly, six times more likely to develop diabetes and heart disease.
That is the conclusion reached by researchers from Imperial College London, whose work was recently published in the journal Nature Genetics. Their discovery may explain why people who work the night shift, often face Type 2 diabetes and heart disease .
A study by British scientists attended nearly 20,000 volunteers. It was found that in a group at particular risk are people who have had one of the four specific gene variations. And it promises the creation of personalized therapy. According to scientists, "spoiled" a protein called MT2 may interfere with communication between our circadian rhythms and produce the hormone insulin, which leads to failures in monitoring level Blood sugar . What causes and development Type 2 diabetes .
Blood sugar It refers to one of the many processes that regulate the human biological clock. The researchers found the effect of this key component in the biological clock gene affects the risk of developing diabetes. They were able to detect rare variations MT2 having a much greater effect than the more common variations detected previously.
Although each mutation is rare, they meet each person in his DNA. Scientists hope to compile a complete catalog of the genetic mutations that will more accurately assess the risk of developing a disease.
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